• Research Questions

  • What is the role of ABL and AKT protein kinases in synaptic transmission and plasticity & memory formation?

  • How protein phosphorylation affects memory engram related gene expression?

  • What is the mechanism of Alzheimer’s disease related amyloid beta peptide effect on synaptic activity/plasticity?

  • How electromagnetic radiation may affect protein aggregation in neurodegenerative diseases? – in collaboration with the NITR (Dr. I. Koman, head)

  • How interplay aging-related cognitive impairments and depression? – in collaboration with Prof. A. Pinhasov

  • How can neurodegenerative diseases be diagnosed by synaptic pathology identification high-throughput approach? – in collaboration with Dr. E. Perlson

  • Can be neural coding/information processing quantum based?

  • Is spatial mapping of memory the major role of hippocampus?

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• Methodologies used

  • Electrophysiology: patch clamp in cell cultures and slices, field recording ex vivo and in vivo in anesthesized and freely moving animals, LFP, EEG

  • Optical Imaging

  • Optogenetics

  • Behavioral Neuroscience

  • High-throughput methods: mass-spectrometry, proteomics, transcriptomics, bioinformatics

  • Biochemical methods

  • Theoretical Neuroscience and Biophysics

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• Keywords

  • ​Synaptic transmission, synaptic plasticity, signal transduction, learning and memory, neural network, information coding, neurodegenerative diseases, protein kinases

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• Courses for Advanced Neuroscience Study

  • Biophysics of Excitable Tissue

  • Synaptic Transmission and Plasticity

  • Molecular and Functional Mechanisms of Learning and Memory

  • Molecular Mechanisms of Neurodegenerative Diseases

  • Neuropharmacology

• Chairman, The Integrative Brain Science Center – Ariel (IBSCA)

• Coordinator, Advanced Neuroscience Study Program

• Head, Laboratory of Molecular & Functional Neurobiology