Unfolding the Mystery of our Brain and Mind
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Research Questions
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To examine the clinical and neuropathological effects of running protocols in a clinically relevant model of Multiple Sclerosis (Experimental Autoimmune Encephalomyelitis; EAE);
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To define the most effective training protocol inducing systemic immune-modulation and direct neuro-protection in EAE;
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To elucidate the molecular and cellular mechanisms underlying the peripheral immune-modulatory and neuroprotective effects of exercise training.
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Methodologies used
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Animal Models for Neurodegeneration
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Clinical Assessments
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Behavioral Tests
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Histopathological Analyses
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Cell Cultures
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Cell Isolation Methods (FACS, MACS)
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Keywords
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Physical Exercise, Immunomodulation, Neuroprotection, Multiple Sclerosis, Experimental Autoimmune Encephalomyelitis
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Courses for Advanced Neuroscience Study
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Neuroanatomy
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Exercise is Medicine for Brain
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Regenerative Medicine for Neurodegenerative Diseases
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Physical Therapy Department
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Head, Laboratory of Neuroimmunology, Neuroregeneration and Physical Exercise
Phone: +972-54-4755058
Website:
http://www.ariel.ac.il/sites/ofirae
http://www.ariel.ac.il/research/scnd
Email: ofirae@ariel.ac.il